Deadliest allergy in the world is often considered to be anaphylaxis from food, insect stings, or drugs, as anaphylaxis can be fatal within minutes if not treated with epinephrine. Among food allergies, peanut allergy is one of deadliest because it is common, can cause severe anaphylaxis from trace amounts, and is leading cause of food allergy deaths. Other deadly allergies include bee and wasp sting allergy, which can cause fatal anaphylaxis, and drug allergies like penicillin allergy. Latex allergy can also cause fatal anaphylaxis but less common. In terms of allergy that causes most deaths worldwide, anaphylaxis from any cause is medical emergency with mortality if untreated, but food induced anaphylaxis, especially peanut and tree nut allergy, is often cited as deadliest food allergy. Insect sting anaphylaxis also causes many deaths. So there is no single deadliest allergy, but anaphylactic reaction is deadliest type of allergic reaction, and peanut allergy is among deadliest food allergies due to severity and prevalence, requiring strict avoidance and epinephrine auto injector. All allergies that can cause anaphylaxis are potentially deadly if not promptly treated.
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