Touching dry termite droppings (frass) with your bare hands is generally not toxic or poisonous, and it will not cause chemical burns or systemic illness. However, because frass consists of tiny, pellet-like digested wood waste mixed with dust and fungal spores, handling it without gloves can occasionally cause minor skin irritation or trigger allergic reactions in sensitive individuals. It is best to sweep it up wearing gloves and a dust mask.
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