The primary difference between PrEP and PEP lies in their timing and purpose relative to potential HIV exposure. PrEP stands for Pre-Exposure Prophylaxis, which is taken consistently before any potential exposure to prevent infection from occurring in high-risk individuals. PEP stands for Post-Exposure Prophylaxis, which is an emergency medical treatment taken after a potential, single-instance exposure to HIV, such as a condom break or sexual assault. PEP must be started within seventy-two hours of exposure and continued as a twenty-eight-day course to stop the virus from establishing a permanent infection.
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