Missing a single daily dose of oral PrEP is generally not catastrophic for individuals taking the medication continuously, but consistency remains vital for maintaining peak protective drug levels. Daily oral PrEP builds up a high concentration of medicine in body tissues over several days, providing a buffer against occasional missed doses. However, repeatedly missing doses reduces its overall effectiveness and leaves your immune system vulnerable. If you miss a pill, you should take it as soon as you remember, but never double up on doses to make up for the missed pill without consulting your doctor.
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