What gets rid of spiders permanently?

What gets rid of spiders permanently requires integrated approach focusing on prevention, exclusion, and habitat modification, as no single method eliminates spiders forever because they can re-enter from outdoors, but you can greatly reduce and keep them away long term. Permanent spider control includes sealing entry points, caulk cracks around windows, doors, baseboards, and foundations, install door sweeps and screens, and repair torn screens to prevent entry. Keep home clean and clutter free, vacuum regularly including corners, under furniture, closets, and basements to remove spiders, webs, and egg sacs, and dispose vacuum bag outside. Reduce prey by keeping outdoor lights off or using yellow bug lights that attract fewer insects that spiders feed on, and keep food sealed to reduce flies and cockroaches. Declutter storage areas, remove cardboard boxes where spiders hide, and store items in sealed plastic containers. Trim vegetation, remove leaf litter, wood piles, and debris near house that provide spider habitat. Use natural deterrents like peppermint oil spray diluted around windows and doors, though evidence limited. For severe infestations, consider professional pest control that applies residual insecticides to cracks and perimeters. No method guarantees permanent elimination because spiders are part of ecosystem and new ones will appear, but consistent exclusion, cleaning, and reducing prey keeps numbers very low permanently with ongoing maintenance.