What is the enemy of bed bugs?

The enemy of bed bugs includes natural predators, environmental conditions, and human control methods that kill them at all life stages. Natural enemies include spiders, cockroaches, ants, mites, and centipedes that may prey on bed bugs, though they do not control infestations effectively. The most effective enemies are high heat, as bed bugs die at temperatures above 113 degrees Fahrenheit sustained for 90 minutes, so professional heat treatment heating rooms to 120 to 135 degrees for several hours kills 100% of bugs and eggs, and washing and drying bedding and clothing on high heat for 30 minutes. Cold can kill but requires below 0 degrees Fahrenheit for 4 days, which is less practical. Desiccant dusts like CimeXa and diatomaceous earth are enemies that dehydrate bugs over days when applied to cracks. Encasements are enemies that trap bugs and starve them over 12 months. Vacuuming physically removes bugs and eggs. Professional insecticides, though resistance is common, include residual pyrethroids, neonicotinoids, and insect growth regulators that prevent reproduction. The biggest enemy is integrated pest management combining heat, encasements, vacuuming, interceptor traps, and professional follow-up treatments two weeks apart to kill newly hatched eggs. No single natural predator controls infestations, so human methods are primary enemies.