The most effective way to disinfect your entire house is to use a systematic two-step process of cleaning first then disinfecting, focusing on high-touch areas, with proper ventilation and protective equipment. Start by decluttering and cleaning all surfaces with soap and hot water to remove dirt and grease, because dirt blocks disinfectants, using HEPA vacuum for dust and allergens. Then disinfect high-touch surfaces like doorknobs, light switches, faucets, countertops, and electronics with an EPA registered disinfectant such as diluted bleach at 1000 ppm, 70 percent alcohol, or accelerated hydrogen peroxide like Oxivir, following label contact time where surface must stay wet for 30 seconds to 5 minutes to kill germs including COVID and flu. For floors, use steam cleaner that reaches above 212F to kill microbes without chemicals. For bathrooms and kitchens, use bleach-based disinfectants for sinks and toilets. For laundry, wash with hot water above 140F and add disinfectant laundry sanitizer. For air, instead of spraying chemical disinfectants that can irritate lungs, use True HEPA air purifiers and open windows for cross ventilation to dilute airborne germs, similar to how hospitals use HEPA filtered negative air machines in isolation rooms. Wear gloves, mask, and ensure good ventilation during disinfection to avoid inhaling fumes. Do not mix bleach with vinegar or ammonia as it creates toxic gas. Focus most effort on areas where sick person spent time if someone was ill with airborne disease that required negative pressure in hospital.
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