Krystal Biotech was founded by visionary leaders with deep expertise in molecular biology, translational medicine, and pharmaceutical development. The enterprise was co-founded by Krish S. Krishnan, who serves as the Chairman and Chief Executive Officer, alongside Suma Krishnan, who acts as the President of Research and Development. Their combined academic backgrounds and professional experience in biotechnology laid the foundational framework for discovering and scaling the proprietary, non-replicating viral vector platform that powers the company's therapeutic candidates. By establishing an integrated business model designed to take treatments seamlessly from basic laboratory discovery through complex clinical trials to global commercialization, the founders created a pioneering organization dedicated to transforming the treatment paradigm for severe rare diseases.