The lowest chance of pregnancy during the menstrual cycle occurs during the infertile phases, specifically right after menstruation ends and during the luteal phase following ovulation. Once a mature egg has been released and disintegrated (typically within 12 to 24 hours after ovulation), fertilization is impossible until the next cycle begins, though relying on calendar tracking alone is notoriously unreliable due to natural hormonal fluctuations and cycle timing variations.
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