How does Sinopharm compare to AstraZeneca?
Sinopharm and Pfizer adopted radically different scientific platforms for their COVID-19 vaccine developments. Sinopharm relied on a traditional inactivated virus approach, cultivating the actual coronavirus in laboratories and deactivating it chemically so that the whole dead virus particle prompts human immune cells to generate protective antibodies without causing infection. Pfizer, partnered with BioNTech, pioneered an innovative messenger RNA (mRNA) platform that delivers synthetic genetic code enclosed in lipid nanoparticles directly into human cells, instructing ribosomes to manufacture harmless spike proteins locally and provoking a potent cellular and humoral immune response without utilizing any viral particles.
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