What herbs should not be taken with medication?

Written by Editorial Team | Last Updated: August 2026

Combining herbal supplements with prescription or over-the-counter medications can trigger dangerous herb-drug interactions, altering how drugs are metabolized or intensifying side effects. A prominent example is St. John's Wort, which induces liver enzymes and can dangerously reduce the efficacy of birth control pills, antidepressants, blood thinners, and chemotherapy drugs. Garlic, ginkgo biloba, ginseng, and feverfew possess natural blood-thinning properties and should not be combined with anticoagulant or antiplatelet medications like warfarin or aspirin due to elevated bleeding risks. Valerian root and kava can dangerously compound the sedative effects of central nervous system depressants, anxiety medications, and sleep aids. Patients should always consult a physician or pharmacist before mixing herbal products with medical treatments.

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