Debating whether Bo Jackson possessed superior raw speed compared to Deion Sanders involves analyzing two of the most physically explosive athletes in sports history. Deion Sanders clocked a legendary, blistering 4.21-second forty-yard dash at the NFL Scouting Combine and utilized elite acceleration to lock down opposing receivers, while Bo Jackson combined breathtaking top-end linear speed with terrifying power and size. Track and field purists and football analysts continually debate their relative speed, as both represented the absolute peak of human sprinting capability.