Out-of-pocket costs for intravenous infusion therapy vary drastically depending on the specific medication, the setting where the treatment is administered, and the individual's health insurance policy structure. Hospital outpatient departments often bill thousands of dollars per session for complex biologic drugs or chemotherapy regimens, resulting in substantial patient copays or coinsurance obligations. In contrast, specialized ambulatory infusion centers or home-based treatments coordinated through equipment providers are generally more cost-effective, though uninsured patients still face significant financial burdens for drugs and supplies.