Yes, a National Basketball Association player has scored 100 points in a single regular-season game, a legendary feat accomplished by center Wilt Chamberlain on March 2, 1962. Playing in Hershey, Pennsylvania, Chamberlain achieved the unbreakable record by dominating the paint and shooting frequently from the field and the free-throw line. To this day, his iconic 100-point performance stands alone as the ultimate individual scoring milestone in professional basketball history, with only Kobe Bryant's 81-point game coming reasonably close in the modern era.