Medicare coverage for Qbrexza, a topical medicated cloth prescribed for primary axillary hyperhidrosis, varies significantly depending on the specific Medicare Part D or Medicare Advantage plan enrolled in, as topical treatments often face stringent prior authorization requirements or tier-placement restrictions. While traditional Original Medicare Part A and Part B typically do not cover outpatient prescription drugs dispensed at retail pharmacies, Medicare Part D plans may cover it if specific formulary criteria are satisfied, though many patients rely on manufacturer savings cards or alternative assistance programs to manage out-of-pocket expenses.