While many physicians acknowledge that at-home stool DNA tests like Cologuard help increase screening rates among reluctant patients, several clinical drawbacks lead some doctors to favor traditional colonoscopies. Cologuard primarily detects existing cancer markers rather than preventing disease because it often fails to identify early-stage precancerous polyps. Additionally, it carries a notable false-positive rate that mandates costly, stressful follow-up colonoscopies, whereas a standard colonoscopy allows doctors to find and remove polyps during the initial procedure.
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