Strict quarantine or total social isolation is generally unnecessary for individuals with shingles, but sensible precautions are mandatory to protect vulnerable people. Because the fluid inside open blisters contains the live varicella-zoster virus, you must keep the rash securely covered with clean clothing or sterile dressings whenever you are around others. You should strictly avoid all direct physical contact with pregnant women who have not had chickenpox, newborn infants, and anyone with a compromised immune system until all blisters have fully crusted over.
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