Yes, quo is a playable Scrabble word and is accepted in official Scrabble dictionaries in North America and internationally. Quo is listed in the Official Scrabble Players Dictionary and in Collins Scrabble Words, which is used outside North America. It is a short but valuable word because it contains a Q without needing a U, making it extremely useful when you have a Q tile and no U tile. Quo is defined as a noun meaning something said, short for quid pro quo, or in medicine, a slang term related to quid. In Scrabble, quo is worth 11 points before premium squares, with Q worth 10 and O worth 1, or more with bonus squares. It is often played to get rid of a Q for decent points while keeping the board open. Other Q without U words that are also valid include qi, qat, suq, and tranq, but quo is one of the more commonly played because it is easy to place. Tournament players memorize Q without U words because Q tiles can otherwise be difficult to play. So if you have Q, O, and a place to play, quo is a legal and strategically smart play in Scrabble and Words With Friends.
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