Gaining undergraduate admission to Duquesne University is generally considered moderately accessible rather than highly restrictive, with an acceptance rate typically hovering between 75 and 85 percent. The university utilizes a holistic review process that evaluates high school grade point averages, curriculum rigor, letters of recommendation, and optional standardized test scores. While competitive programs like nursing and pharmacy demand stronger academic profiles, the overall admissions approach is welcoming to qualified applicants.