Performing a Renuvion sub-dermal tightening procedure is typically a one-time treatment per targeted anatomical region because the helium plasma and radiofrequency energy induce long-lasting structural collagen remodeling and tissue contraction. While touch-up procedures or treatments on entirely different body zones can be evaluated by a plastic surgeon after complete healing, repeating the procedure on the exact same tissue area is rarely required or standard practice due to the durable nature of the initial sub-dermal contraction results.