No, you should never pour Drano or any other commercial lye-based chemical drain cleaner down your air conditioning condensate drain line. Commercial chemical drain openers are specifically formulated to dissolve organic hair and grease clogs in kitchen and bathroom plumbing traps, but they are entirely unsafe and inappropriate for HVAC condensate systems. These harsh chemical products generate intense exothermic heat during their chemical reaction, which can easily melt, warp, or crack standard PVC condensate pipes and drain pans. Furthermore, if the clog does not clear immediately, the caustic chemicals will sit inside the lines and release toxic fumes that can be sucked into your ductwork and circulated throughout your entire living space, creating serious health hazards for your family. Instead of Drano, use white vinegar, hydrogen peroxide, or a wet-dry vacuum to safely clear the line.
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