Medical guidelines and emergency use protocols indicate that if you have recently received a COVID-19 vaccine, PEMGARDA should generally be administered at least two weeks after your vaccination to allow your immune system adequate time to process the active immunization. Conversely, if you have already received a PEMGARDA infusion, health providers typically recommend waiting an appropriate interval before getting a subsequent active COVID-19 vaccine dose so that the passive monoclonal antibodies do not blunt your body's active immune response. Patients should always consult their managing physician or immunologist to schedule vaccinations and prophylactic infusions safely around their personal health needs.